Sunday, May 5, 2013

Couples Trying to Conceive

THURSDAY, Oct. 4 (HealthDay News) -- Researchers who developed a mathematical model to help predict a couple's chances of becoming pregnant say the method may help determine how long couples should wait before seeking medical help to achieve pregnancy.

The method determines the probability of conception within the next month by using the number of menstrual cycles that have occurred during the time a couple has been trying to conceive. For example, the U.K. researchers found that a 35-year-old woman who has been trying for six months to get pregnant has only a 10 percent chance of conceiving within the next month.

In comparison, the number of months required to reach a conception chance below 10 percent is 10 months at age 30 and 13 months at age 25, according to the study appearing online Oct. 4 in the journal PLoS One.

"Many couples are not aware that chance plays a big role in getting pregnant. People expect to get pregnant when they want to, so finding out that it isn't happening can be a shock. Approaching a doctor about such a personal matter is daunting, so knowing when is the right time to start investigations would be a useful step forward," study author Geraldine Hartshorne of Warwick Medical School, said in a University of Warwick news release.

"We can't work out exactly when, or if, a woman will become pregnant -- but this analysis can predict her chances, and give a percentage estimate of pregnancy in the next cycle," she added.

Common wisdom has been that couples who are trying to get pregnant should have regular sex for a year before seeking help, but this study shows that age also affects this decision.

"Comparatively few young couples have low fertility, and so for these couples, the most likely reason for failing to conceive in the first few cycles is simply bad luck. There is quite a good chance of conception if they keep trying," study author Peter Sozou, of the London School of Economics, said in the news release.

"But older couples are more likely to have low fertility, so it's more likely for them than for younger couples that failure to conceive after a few months is due to low fertility," he noted.

More information
The U.S. National Institute of Child Health and Human Development
has more about infertility/fertility.
Copyright © 2012 HealthDay. All rights reserved.

Acupuncture & Breast Cancer

FRIDAY, Nov. 2 (HealthDay News) -- Offering breast cancer patients a relatively short regimen of acupuncture alongside standard treatment can help alleviate some of the crippling fatigue that often accompanies the disease, according to a new study.
The magnitude of help that patients undergoing acupuncture experienced was deemed by the study team to be "both statistically and clinically important."
"I am quite excited with these results," said study lead author Alex Molassiotis, a professor of cancer and supportive care with the school of nursing, midwifery and social work at the University of Manchester, in England. "They provide some good evidence of an effect of acupuncture for the management of a very debilitating and burdensome symptom for patients."
"The addition of a new treatment approach gives patients and health professionals more options," Molassiotis added, noting that the range of options specifically designed to
address fatigue issues among cancer patients has been limited.
The study appeared online Oct. 29 in the Journal of Clinical Oncology.
More than 40 percent of breast cancer patients experience significant cancer-related fatigue, according to background information included in the study. For some patients the problem may persist at a moderate or even severe level for years following the cessation of treatment.

To explore the potential of acupuncture treatment, the authors focused on more than 300 women with breast cancer who were being cared for as outpatients at one of nine health care facilities across the United Kingdom.

At the time of the study, participants had been diagnosed with either stage 1, 2 or 3 breast cancer, and all had been experiencing at least moderate levels of fatigue for an average of 18 months. Most were white, and their average age was 53. For a six-week period, all patients continued to receive the same care they had been receiving before the study, and all were additionally given an information booklet that tackled the issue of fatigue management.

However, more than 200 of the patients also were randomly chosen to undergo weekly 20-minute acupuncture sessions that involved needle placement at three different entry points. By the end of the six-week period, those who had received acupuncture appeared to fare better on every measure of fatigue that the team assessed.

Specifically, those in the acupuncture group reported feeling notably better than the "usual-care" group in terms of overall fatigue, physical and mental fatigue, anxiety and depression levels, functional well-being, emotional well-being, social functioning, and overall quality of life.

"Acupuncture is a complementary therapy that not only can have direct effects on the symptom experience of patients, but also ... provide the opportunity [for] patients to be more involved with their symptom management and empower them more," Molassiotis said. "Patients also like 'natural' and 'traditional' approaches to health management."

"[However], we still do not understand how acupuncture may work to manage fatigue," he acknowledged. "Within the results may also be a so-called placebo effect, which is common in many complementary therapies. So in future work we need to look into objective and physiological outcome measures, too, although the patient-reported outcomes used in the current trial are equally very important."

Dr. Laura Kruper, director of the Cooper-Finkel Women's Health Center and chief of the breast surgery service at the City of Hope Cancer Center in Duarte, Calif., described the British effort as both "well done" and "strong."

"Acupuncture has been used in a variety of settings within medicine, such as to control chemotherapy-related nausea, post-operative nausea, migraines and chronic pain," she said. "It is still not exactly known how acupuncture works, but that does not mean it does not have therapeutic benefit."
But, while noting that "many patients turn to complementary therapies to bridge the gaps that Western medicine does not fill," Kruper stressed the need "to ensure that these therapies are safe, effective and reliable."

"In the world of medicine, we rely on investigational studies to guide our treatment decisions so that we provide evidence-based medicine," she said. "Complementary therapies need to undergo the same rigorous tests that Western medicine does. This study was exemplary in that it was conducted with adherence to the principles of scientific method, and hopefully a study like this will be the first of many."

Although the study found an association between acupuncture and reduced fatigue in breast cancer patients, it did not prove a cause-and-effect relationship.

More information
For more on acupuncture, visit the U.S.
National Center for Complementary and Alternative Medicine

Copyright © 2012 HealthDay. All rights reserved.